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Old 07-21-2009, 06:37 PM   #31 (permalink)
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The Bro-understanding of insulin seems to be what T-mag bases its supplement development process on.

Insulin, and by extension carb intake/blood glucose, does not positively affect protein synthesis at any stage of the process. Having full glycogen stores will limit protein breakdown and it will help curb inflammation (both mainly via AMPK's signal cascade), but in and of itself, neither carb intake nor insulin levels are inherently "anabolic" - and definitely not to the degree nor in the manner they're claiming.

The whole insulin and post-workout carb obsession is all based on the studies showing roughly a three trillion percent improvement in gains after taking a protein shake and/or AA+CHO shake post-workout. Sounds good, until you realize those studies were all done in fasting subjects. Protein loss is going to be maximized during a fast, and training during a fast makes it even worse temporarily. Of course a large hit of AA+CHO is going to massively reverse that.

If you're eating regularly, as anyone hoping to add muscle should be, those conditions simply don't apply. You'll have a constant supply of AA in the blood and relatively full glycogen stores, and thus neither the protein loss nor the resulting LOADED ANABOLIC SURGE!!!!! will be as substantial.

If they want to provide research citations to prove otherwise, great. I'm not holding my breath; they don't need research when they've got T-Hype(TM).

For my money, I get a good hit of fast-digesting whey before a session and then slow-acting protein (usually milk + whey) after. If I need extra carbs I throw in a little, but usually I'm fine without. If I were trying to gain weight I'd add some gatorade or something beforehand.
yeah, I've read up to several places now that the anabolic effect of insulin is highly overrated, and that it reaches its max anabolic effect just slightly above fasting level.

One thing I've always wondered is the "insulin pumps AA into muscle" thing. Now, as I understand it, it's actually extracellular AAs that signal protein synthesis, but I guess you have to get the AAs into the cell for them to actually be substrates, but how important is insulin in this process? and how is it done without insulin? For some reason, the mighty google has failed me on this.. maybe I'm just not typing the right words, but..
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Old 07-21-2009, 06:40 PM   #32 (permalink)
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I've actually become slightly obsessed with how the OCD sugar dosing scheme might affect the human body. It seems to be layering on different levels of different sugars so that they all peak about the same time, and then introducting protein during the workout. The maxed out regimen is at least 1500 cals or so, which might be in itself the reason for mass gain during the program. Dixie cups full of sugar might work as well.
First of all damn you guys for making me read that cess-pit of a website

Second of all, holy mother of LOLZ at the "peri-workout protocol". That's the biggest load of horeshit I've seen since the Kentucky Derby.

Turns out when you eat a ton of sugar and protein before and during your workout, you can train hard and you put on weight?

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I am very interested to see the training regimen. Many of CT's schemes seem to be complicated. This could be space shuttle launch complicated.
I'm interested from a "need a good laugh" standpoint.

Thib's training recommendations were solid many a year ago, then he just lost touch with reality*.

* By reality, I mean "how naturals should train"
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Old 07-21-2009, 06:43 PM   #33 (permalink)
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One thing I've always wondered is the "insulin pumps AA into muscle" thing. Now, as I understand it, it's actually extracellular AAs that signal protein synthesis, but I guess you have to get the AAs into the cell for them to actually be substrates, but how important is insulin in this process? and how is it done without insulin? For some reason, the mighty google has failed me on this.. maybe I'm just not typing the right words, but..
AMPK -> GLUT4 -> shit gets into cells if it's needed

Insulin need not apply. It helps, mainly by increasing GLUT4 expression, but it's not mandatory.

I'd consider AMPK to be the main determinant, as it's ultimately going to regulate how much actually gets into the muscle.

Of course once muscular and liver glycogen stores are full, I'll give you one guess where all those sugar calories go.

And yes, fat cells will store calories w/o insulin as well, thanks to ASP.
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Old 07-21-2009, 07:19 PM   #34 (permalink)
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so glut 4 gets amino acids into the cell aswell? thanks.

Of course, during exercise AMPK will increase the GLUT4 expression, but what about when you're not exercising? Is insulin then important to increase glut4 expression to shuttle AAs into the cell during rest, or can that be achieved at a sufficient rate from just normal levels of insulin?

Sorry for asking so many question, but you seem to have a firm grasp on this sort of thing, so I figured I'd try to take advantage of you.
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Old 07-21-2009, 07:26 PM   #35 (permalink)
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GLUT4 is the glucose transporter. I'll actually have to go look RE: AA transport, but as far as I recall uptake of AA is very similar. Insulin helps, but is not mandatory. Muscle contractions and glycogen depletion will both increase nutrient uptake in muscle, with or without insulin. Insulin just modulates the process.
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Old 07-21-2009, 09:28 PM   #36 (permalink)
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j/k. Please continue. It sure beats the hell out of "My Anaconda don't want none unless you got guns, hun!".
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Old 07-22-2009, 12:41 AM   #37 (permalink)
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you can do bi curls or pullups, but please don't lose that pump
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Old 07-22-2009, 01:19 AM   #38 (permalink)
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wow. i can't believe i didn't look at the site until now.

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Thib's training recommendations were solid many a year ago, then he just lost touch with reality*.

* By reality, I mean "how naturals should train"
WHAT?!

According to Tim Patterson...

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Tim Patterson and Christian Thibaudeau have taken this strategy to an entirely new level, except that they don't need the use of drugs.
note: they don't need drugs... but they're always nice.

did we really need 4 pages of this drivel? Couldn't people just skip right to page 3? I mean, the suspense was really killing me that they built throughout the video and 2 pages, i'm glad they didn't wait until page 4 to tell me the stuff because i probably couldn't take it.

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"That's what I did with Anaconda. I formulated it with one and only one type of individual in mind, and for only one, very specific purpose:

"I designed Anaconda exclusively for our elite-level bodybuilders, the ones we work with, like Christian. And I designed it to deliver the end-all-be-all, most-potent anabolic load possible.
the children over at t-rag will probably be sorely disappointed when their bottle of Anaconda is not loaded with Dbol.

More disturbing is the name. One COULD say, that Christian was consuming Tim Patterson's Anaconda, huh?
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Old 07-23-2009, 04:23 AM   #39 (permalink)
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More disturbing is the name. One COULD say, that Christian was consuming Tim Patterson's Anaconda, huh?
Christian consumes tims anaconda, and tims anaconda provides the end-all-be-all, most-potent anabolic load possible.
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Old 07-23-2009, 08:10 AM   #40 (permalink)
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Thib's training recommendations were solid many a year ago, then he just lost touch with reality*.

* By reality, I mean "how naturals should train"
Bingo!
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Old 07-23-2009, 11:25 AM   #41 (permalink)
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Best title of the year.
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Old 07-23-2009, 10:25 PM   #42 (permalink)
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I would have gone with "Hey PMDL, do you want my big black Anaconda?"
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Old 07-24-2009, 04:56 PM   #43 (permalink)
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That would have got me here so fast
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Old 07-24-2009, 06:05 PM   #44 (permalink)
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Read the article on t-rag today, its gold!
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bar x F hahaha
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