I have done heavy negatives in the past to get a 'feel' for the weight, and remove the shock of a weight that's new. I'm sure they are useful for other things as well, but I pretty much do partial movements now instead of negatives. Things like quarter squats, rack DLs, and rack bench let me do more weight than normal, but also let me get the feel for pushing it back up (even if it's under a limited range of motion).
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