http://www.urologytimes.com/urologyt....jsp?id=157755
http://www.jnj.com/news/jnj_news/20050523_141524.htm
http://www.urologytimes.com/urologyt...ID=1&sk=&date=
You may get tired of those suppertime ads for Viagra, Levitra, and Cialis and these fairly new drugs have been the mainstays of late night TV comedy, but there’s a reason men buy them.
The major varieties of male sexual dysfunction number just three. (I don’t count not being able t have sex without the guy clutching the teddy bear he got at age 3). There’s deficient or absent libido: a guy just doesn’t want sex much or want much sex, not in comparison with how constantly horny he was somewhere back in time. Then there’s what used to be called “impotence,” but now goes by “Erectile Dysfunction” or plain “ED.” The euphemism is an improvement. If you’re impotent, it’s you that’s the problem. If it’s ED it’s something you’ve got. ED is likely to come on a guy a little later in life, but the third kind of dysfunction can strike very early, like the first time a young guy has an honest to God opportunity to have sexual intercourse with a willing partner. This guy, at 18, may have a raging libido. He may be able to have 8 erections in 4 hours, but the deed is scarcely begun before it’s over. If the brevity of intercourse bothers him and his companion, he’s suffering from “Premature Ejaculation” or PE. “Premature” means not enough time, and it raises the questions, how much is too little, how much is okay. Urologists lately have come up with a term of measurement--Intravaginal Ejaculatory Latency Time or IELT. It’s the length of time between insertion of the penis into the vagina and the moment of male climax. It’s measured with a stop watch by either partner. There are degrees of PE. A IELT of 15 seconds is PE; anything under 2 minutes is still PE. The longer the IELT the better; at 7 minutes or longer, whatever one’s problems might be, premature ejaculation is not among them.
We all know that when one of these problems arise, we should see our doctors and discuss what’s wrong. But that’s very hard to do. Most of us fudge when a white coat is talking to us. And years ago, when my doctor got to the question, “How’s your libido?” I resisted saying none of your damned business. So I said, “Just fine.” What I meant was, probably as good as I should expect at age 64. The fires were banked. I still got horny, but not very and not very often.There came a point when my doctor knew that whatever I said, my libido had to be almost non-existent. He put me on Androgel, on testosterone replacement therapy. The next day I started paying attention to women’s figures. I got a little but unmistakable warmth in the inguinal region. Like an engine that hadn’t been started in years, my libido roared into action. Other stuff happened, too. I started working out in a gym. I took up kayaking. Depression vanished. I lost 40 pounds. I felt like I’d also lost 30 years. My strength has steadily increased right up until today. And when my doctor asks how my libido is, I reply that it’s a bit stronger than is really convenient sometimes.
First came Testosterone Replacement Therapy (TRT) and Androgel. It brought me what DuPont used to call Better Living through Chemistry. A few years later, the blue pill Viagra arrived, then Levitra, and then Cialis. I didn’t need them, but I did give them a try, more out of curiosity than need. I have no doubt but that they’re godsends for guys who do need help obtaining or keeping an erection. Meanwhile, however, the guys with unsatisfactorily abbreviated IELTs have been neglected pharmacologically.
But help is on the way. Check out the links above for more details, but yesterday in San Antonio at the 100th Annual Meeting of the American Urological Council data was presented showing that men taking dapoxetine hydrochloride for treatment of PE showed significant improvement in sexual function, including control of ejaculation, greater satisfaction in sexual intercourse for both men and their partners, and increases in intravaginal ejaculatory latency time--increases of three- or fourfold. That could be from 2 minutes to 6 or 8.
The FDA is currently reviewing a new drug application for dapoxetine. If approved, it would be the first prescription product indicated for the treatment of PE.
I wonder just a bit, however. Lately the FDA has taken some moral and religious stands against medicines with sexual applications. Jerry Falwell probably hates the idea that a lot of guys with poor sex lives because they’re too quick with the trigger might quadruple their moments of pleasure. He might get people stirred up about this immoral unchristian dapoxetine stuff and try to block it. Unless, of course, old Jerry himself is a bit short in the IELT department. Hmm.
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