ha, i just posted this at the mh board from the facts about fitness
Researchers from Iowa State University tested the effects of one of these products - known as ANDRO-6 [8]. Along with 300mg of androstenedione, ANDRO-6 also contains DHEA and tribulus terrestris (which are both meant to boost testosterone), together with two substances that are supposed to remove excess estrogen from your body (chrysin and indole-3-carbinol). In theory, a product like ANDRO-6 would boost testosterone while also minimizing the production of estrogen. Sounds great, doesn't it?
Here's what happened.
The researchers took 20 test subjects and split them into two groups. The first group used ANDRO-6 in combination with a resistance training programme. Group two followed an identical exercise programme, but used a fake supplement. Neither the researchers or the subjects knew which was which.
Although the ANDRO-6 users experienced a slight increase in testosterone, it obviously wasn't enough to affect muscle growth. However, the researchers did find a large rise in estrogen levels, which occurred despite the addition of various ingredients designed to "block" estrogen production. As in previous studies, there was also a drop in HDL (the "good" cholesterol) - representing a 10-15% increase in the risk of heart disease.
"The addition of these herbal extracts", say the researchers "does not result in increased serum testosterone concentrations, reduce the estrogenic effect of androstenedione, and does not augment the adaptations to resistance training".
In other words, the stuff didn't work.
The bottom line
There is no evidence to suggest that oral androstenedione (in doses of up to 300mg per day over a 12-week period) has a positive effect on muscle growth -- even when it's combined with estrogen scavengers. Definitely one to avoid.
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