clenbuterol-anabolic agent

[10iscoach]

Clenbuterol, cousin to albuterol, is a drug developed to treat airway diseases (e.g. asthma). its chemical action in the body is to activate beta-2 receptors in tissue. although the drug is useful in the treatment of airway disease, in the 1980's it was discovered that Clenbuterol is a powerful anabolic agent in skeletal muscle. In a 14 day treatment of animals with clenbuterol (2mg/kg/day) results in a 10-20 percent increase in muscle mass (yang, 1989, multiple actions of beta-2 agonists on skeletal muscle) The muscle growth observed in animals following treatment with clenbuterol is a true hypertrophy and does not involve hyperplasia. further, the time course of clenbuterol induced muslce hypertrophy is rapid with muscle growth beginning within two days after commencement of treatment.
at present, clenbuterol is not a legal drug in the United States and is a banned substance for use in International ahtletic competition. Further, use of the drug may also pose serious health risks. because high doses also activate beta-1 receptors, clenbuterol increases heart rate and can cause serious arrythmias.

[Bill Hartman]

In super-humans (drug enhanced bodybuilders) Clenbuterol is typically used for its anti-catabolic/thermogenic qualities.

It suppresses muscle wasting effects of cortisol so it may produce a bit of muscle. It also works well post-cycle (steroid cycle) to prevent the loss of muscle from the lack of juice.

Did you want to discuss further?

Bill

[Jean-Paul]

Let's talk about the negative side effects in healthy individuals... are they any?

I know a guy who uses albuterol, I think to increase his endurance. He claims that he just doesn't fatigue as easily, and that he can just keep going and going and going...... I called him an idiot. Does he know something I don't? Is it similar to Clen?

[Bill Hartman]

They're both beta-2 agonists.

Clen is taken orally to the best of my knowledge. Albuterol is inhaled and is a bronchodilator (it relaxes bronchospasm). Those of use with asthma are good buddies with albuterol.

As a bronchodilator, albuterol may have some benefit for aerobic athletes. I'm not sure how much...it's not something I get concerned about. bryanc may have an opinion on that (not that he used it for such purposes, but more along the lines of him being a smart cookie).

This is from the Family PDR for albuterol:

"More common side effects may include:
Aggression, agitation, cough, diarrhea, dizziness, excitement, general bodily discomfort, headache, heartburn, increased appetite, increased blood pressure, indigestion, irritability, labored breathing, light-headedness, muscle cramps, nausea, nervousness, nightmares, nosebleed, overactivity, palpitations, rapid heartbeat, rash, ringing in the ears, shakiness, sleeplessness, stomachache, stuffy nose, throat irritation, tooth discoloration, tremors, vomiting, wheezing, worsening bronchospasm"

My personal experience shows almost none of the above that I can recall...maybe a little increased heart rate with an O.D. during a particularly difficult asthma attack.

With Clen (based on the experience of some "friends") often causes headaches, high BP, and elevated body temp. Sounds a lot like a caffeine/ephedrine stack although the body temp. increase can be rather dangerous.

Bill

[gardener]

Three of my five grandkids are asthmatic, and one of my two sons has a late-onset case. They all swear by albuterol. (Luckily, the kids are showing signs of growing out of the condition, possibly from being very active in sports.)

When I was in public school back in the 1940s I think I knew one kid with asthma. Polio was much more common. And in Lord of the Flies, there's only one case of asthma among the 50 or so stranded kids. Now it seems to be everywhere, and I've never seen a really convincing explanation for this epidemic. Anybody?

[10iscoach]

their potency is approximately 25% of that of anabolic steroids. They also enhance lipid metabolism, increase lipolysis, decrease fat deposition, and increase lean body mass and the lean-to-fat ratio.

Clenbuterol has the longest half-life of all the commonly available beta-agonists (35 hours, compared with 5 hours for albuterol sulfate) and is considered to be the most potent by athletes . A long half-life may be necessary to produce an anabolic effect, but human studies have shown a 14% to 18% increase in hamstring and quadriceps muscle strength at oral albuterol dosages of 8 mg twice a day (a dose at which most humans have significant side effects). Side effects of clenbuterol are the expected ones for a beta-agonist: tachycardia, palpitations, muscle tension, headache, and dizziness.

Beta-adrenergic agents are most commonly used therapeutically in inhaled form to treat asthma. Approximately 10% to 15% of athletes at most levels of competition have exercise-induced bronchospasm, and an additional few have more severe inflammatory forms of asthma. The use of all beta-adrenergic agents in inhaled form was permitted by the IOC until 1992, when the anabolic properties of these drugs were quantified. At that time, all long-acting inhaled and oral forms, including clenbuterol (available only in Europe and for veterinary use) and salmeterol xinafoate, were banned by the IOC and were classified as "stimulants" and "other anabolic agents." Inhaled albuterol and terbutaline sulfate are permitted by the IOC after approval subject to verified medical indication. Use of salmeterol in inhaled form also is now permitted by the IOC, since studies have demonstrated a negligible anabolic effect (6,17). Clenbuterol was banned by the NCAA in 1993 as an "anabolic steroid," but all other long-acting beta-adrenergic agents are permitted by the NCAA in inhaled form; oral forms are banned as "stimulants." The NCAA allows the use of theophylline and cromolyn.

[dinabol]

It works. Member Hartman stated it is used for it's anti catabolis effects. so, are anabolic steroids which they should be called anti catabolic steroids. They slug it out with cortisol for the receptor sites. does clenbuterol work? oh yeah, and it's very easy to obtain in mexico. All you have to do it claim it as your own and customs will leave you alone. I have found that when you get off clenbuterol you lose the results you gained. so,you must take it regularly. then, tolerance builds. so, be careful. consider cycling it on and off.

[Bond007]

Okay, here goes nothing....

If taking clen for PCT, would you still wait 2 weeks after your last injection before starting it? Also, how well would it work with clomiphene citrate and anastrozole?

I've read more that most "super-humans" use clen for it's thermogenic and anti-catabolic effects than for muscle growth.

[dinabol]

are you using the clomiphene for an LH surge? I would start using clen immediately after your cycle. watch out for the "shakes, but those go away"

[Bond007]

Thanks!

The clomiphene and anastrozole is in case of gyno and PCT to trigger natty "T" production.

[dinabol]

yeah "b*** t((s" those suck. if you cycle right and watch your dose you can avoid the very problem we are talking about. that is also why clen is becoming increasingly more popular. it's very easy to obtain in mexico. customs will leave you alone if you claim it for asthmatic purposes.

[dinabol]

I would only use clomid if I had no other choice for pct. Novladex is the best and most preffered.

[bryanc]

Sorry to be a disturbance, but why exactly are we having this discussion? Or am I the only one who thinks this is not a topic that is keeping with the philosophy of this forum?

[dinabol]

A friend of mine wrote this:
What is Clenbuterol?

Clenbuterol is a beta-2 agonist and is used in many countries as a broncodilator for the treatment of asthma. Because of it's long half life, clenbuterol is not FDA approved for medical use. It is a central nervous system stimulant and acts like adrenaline. It shares many of the same side effects as other CNS stimulants like ephedrine. Contrary to popular belief, Clenbuterol has a half life of 35 hours and not 48 hours.

Dosing and Cycling

Clenbuterol comes in 20mcg tablets, although it is also available in syrup, pump and injectable form. Doses are very dependent on how well the user responds to the side effects, but somewhere in the range of 5-8 tablets per day for men and 1-4 tablets a day for women is most common. Clenbuterol loses its thermogenic effects after 6-8 weeks when body temperature drops back to normal. It's anabolic/anti-catabolic properties fade away at around the 18 day mark. Taking the long half life into consideration, the most effective way of cycling clen is 2 weeks on/ 2 weeks off for no more than 12 weeks. Ephedrine can be used in the off weeks.

Clenbuterol vs Ephedrine vs DNP

Ephedrine will raise metabolic levels by about 2-3 percent and 200mg of DNP raises metabolic levels by about 30 percent. Clenbuterol raises metabolic levels about 10 percent and it can raise body temperature several degrees.

DNP is by far the most effective fat burner but many people will never use it because of the risks associated with it. It also offers no anti-catabolic benefit. Although it does have anti-catabolic effect, ephedrine short half life prevents it from being all that effective.

As far as side effects, Clenbuterol's are certainly milder than DNP's, and some would even say milder than an ECA stack. There is no ECA-style crash on Clenbuterol and many users find it easier on the prostate and sex drive. This may in part be due to the fact that Clen is generally used for only 2 weeks at a time.

Side effects

NAUSEA
NERVOUSNESS
DIZZINESS
DROWSINESS
DRY MOUTH
FACIAL FLUSHING
HEADACHE
HEARTBURN
INCREASED BLOOD PRESSURE
INCREASED SWEATING
INSOMNIA
LIGHTHEADEDNESS
MUSCLE CRAMPS
TREMORS
VOMITING
CHEST PAIN

The most significant side effects are muscle cramps, nervousness, headaches, and increased blood pressure.

Muscle cramps can be avoided by drinking 1.5-2 gallons of water and consuming bananas and oranges or supplementing with GNC potassium tablets at 200-400mg a day taken before bed on an empty stomach.

Headaches can easily be avoided with Tylenol Extra Strength taken at the first signs of a headache. You may need to take double the recommended dose.

Common Uses

Post-Cycle Therapy: Clen is used post cycle to aid in recovery. It allows the user to continue eating large amounts of food, without worrying about adding body fat. It also helps the user maintain more of his strength as well as his intensity in the gym. Diet: Roughly the same as on cycle.

Fat loss: The most popular use for Clen, it also increases muscle hardness, vascularity, strength and size on a caloric deficit. For the most significant fat loss, Clen can be stacked with T3. Diet: A high protein(1.5g per lb of bodyweight), moderate carb(0.5g to 1g per lb of bodyweight), low fat diet(0.25g per lb of bodyweight) seems to work best with Clen.

Alternative to Steroids: Clenbuterol has mild steroid-like properties and can be used by non AS using bodybuilder to increase LBM as well as strength and muscle hardness. Diet: A moderate carb, high protein, moderate fat diet work well.

Stimulant/Performance Enhancement: It can be used as a stimulant, but an ECA stack may be a better choice because of it's much shorter half-life. Diet: To take full advantage of the stimulatory effects of Clen, Carbs must be included in the diet. Keto diet do not work well in this case.

Precautions: Is Clen for you?

The same precautions that apply to Ephedrine must be applied to Clen, although some people find ECA stacks harsher than Clen. It should not be stacked with other CNS stimulants such as Ephedrine and Yohimbine. These combinations are unnecessary and potentially dangerous. Caffeine can be used in moderation before a workout for an extra kick, although its diuretic effects may shift electrolyte balance. Drink more water if you use Caffeine.

What else do I need to know?

Most users that report bad side effects and discontinue use are those who use high doses right at the start of the cycle. The worst side effects occur within the first 3-4 days of use.

A first time user should not exceed 40mcg the first day.

Example of a first cycle:

Day1: 20mcg
Day2: 40mcg
Day3: 60mcg
Day4: 80mcg
Day5: 80mcg(Note: Increase the dose only when the side effects are tolerable)
Day6-Day12: 100mcg
Day13: 80mcg (Tapering is not necessary, but it helps some users get back to normal gradually)
Day14: 60mcg
Day15: off
Day16: off
Day 17: ECA/ NYC stack

Example of a second cycle:

Day1: 60mcg
Day2: 80mcg
Day3: 80mcg
Day4: 100mcg
Day5: 100mcg
Day6-Day12: 120mcg
Day13: 100mcg
Day14: 80mcg
Day15: off
Day16: off
Day 17: ECA/ NYC stack

Do not take Clen Past 4pm and drink plenty of water: 1.5-2 gallons a day.

All brands are not equal when it comes to Clen, different brands will yield different results.

That about covers everything.