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Old 04-10-2008, 10:14 PM   #1 (permalink)
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Default Fat Cells

I read somewhere a while back that if you put on weight your body can increase the number of fat cells it has as well as the size of those cells, but if you loose weight the total number of fat cells in unaffected and the cells just get smaller.

On the other hand... I have also heard that this is BS and that you have X number of fat cells regardless and that the size of the cells can change but that their quantity remains stable.

Which is correct?
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Old 04-10-2008, 10:35 PM   #2 (permalink)
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Cell death doesnt happen very often, but the body is quite adept at forming new adipocytes.
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Old 04-10-2008, 11:27 PM   #3 (permalink)
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Cell death doesnt happen very often, but the body is quite adept at forming new adipocytes.
Does that imply that once you have been fat you can never totally get rid of the fat cells (just make them smaller)?
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Old 04-10-2008, 11:33 PM   #4 (permalink)
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Without extreme measures, yes.
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Old 04-10-2008, 11:49 PM   #5 (permalink)
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Without extreme measures, yes.
Well that sucks!
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Old 04-11-2008, 12:58 AM   #6 (permalink)
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i have no clue at all..

but i would imagine an "unfilled" fat cell... its pretty damn small
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Old 04-11-2008, 08:26 PM   #7 (permalink)
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Well that sucks!

I second that notion. I wish someone would have told me that before I let myself gain 20 pounds last year. I might have taken it a little more seriously. How can you get more fat cells so easily but not lose them with just as much ease? I know you can shrink them down and look great, but I just don't like the idea of carrying arounf all these extra fat cells. I wish I hadn't read that.
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Old 04-12-2008, 02:49 AM   #8 (permalink)
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Liposuction

or

Chemo


are about the best options
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Old 10-01-2009, 06:16 AM   #9 (permalink)
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Oftentimes, people who have been very obese will also be the ones that will gain an enormous amount of water weight when overeating.. is this all because of these 'hungry & empty fat cells' that can now store an enormous amount of water?

In the time I was much fatter I'd gain a lot more water weight than I do now.. it stopped when no longer eating low-carb all the time.. so I wonder, is it more about inflammation than about storage space that makes people retain so much water?

The times I do gain water weight it mostly is associated with having had a ton of fibrous foods & most water seems to be just sitting in the gut..

So, what determines whether or not you're going to have ginormous bloat or not?
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Old 10-01-2009, 10:22 AM   #10 (permalink)
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My understanding -- which may be slightly out of date -- is that it's not the number of fat cells that matters. It's where they are and how they behave. Visceral fat cells are capable of wreaking havoc on your metabolism. I think they send out more than two dozen hormonal signals, some of which encourage you to overeat and enter a state of caloric surplus.

I have no idea why this happens to some people but not others.
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Old 10-01-2009, 11:04 AM   #11 (permalink)
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Of course, the more insulin sensitive you get, the more of the surplus food will go to muscles & draw water into muscles instead of into fat cells.
Inflammation is playing a huge role too..

Complicated stuff..
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Old 10-01-2009, 11:14 AM   #12 (permalink)
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Soon there will be an easier way to kill fat cells.

http://www.plasmetic.com/latest-tren...posuction.html
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Old 10-01-2009, 01:17 PM   #13 (permalink)
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Couldn't find the actual article, but what about this?

http://forum.bodybuilding.com/showth...hp?t=117131421
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Old 10-01-2009, 04:58 PM   #14 (permalink)
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There was also the "woosh" hypothesis that fat cells, once they lose the fat, might temporarily fill up with water, masking fat loss.

The important thing is not to give up.... an empty fat cell is nearly as good as no fat cell at all.

edit: the 'cold therapy' sounds a little bit like frostbite. Yikes.
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Old 10-02-2009, 07:20 AM   #15 (permalink)
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If muscle cells can atrophy and then die off if they're unused as we age, it makes sense that fat cells could die off as well.
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Old 10-02-2009, 12:01 PM   #16 (permalink)
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If muscle cells can atrophy and then die off if they're unused as we age, it makes sense that fat cells could die off as well.
True, but I don't think it's that simple. A lot of things in life would make sense aren't true. Berardi seems to have made a recent discovery to your point though, which I think could be a huge deal.
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Old 10-02-2009, 04:12 PM   #17 (permalink)
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True, but I don't think it's that simple. A lot of things in life would make sense aren't true. Berardi seems to have made a recent discovery to your point though, which I think could be a huge deal.
That was from an Oxygen article in 2007--did anybody find the original source? I ran out of time poking around for it.

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Old 10-02-2009, 10:54 PM   #18 (permalink)
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That was from an Oxygen article in 2007--did anybody find the original source? I ran out of time poking around for it.

Yeah I couldn't find the original either. I looked.
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