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Old 11-06-2007, 02:36 PM   #1 (permalink)
coach hale
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Default low GI vs High GI

Long-term effects of 2 energy-restricted diets differing in glycemic load on dietary adherence, body composition, and metabolism in CALERIE: a 1-y randomized controlled trial.

Am J Clin Nutr. 2007 Apr;85(4):1023-30
SK Das et. al.
BACKGROUND: There remains no consensus about the optimal dietary composition for sustained weight loss. OBJECTIVE: The objective was to examine the effects of 2 dietary macronutrient patterns with different glycemic loads on adherence to a prescribed regimen of calorie restriction (CR), weight and fat loss, and related variables. DESIGN: A randomized controlled trial (RCT) of diets with a high glycemic load (HG) or a low glycemic load (LG) at 30% CR was conducted in 34 healthy overweight adults with a mean (+/-SD) age of 35 +/- 6 y and body mass index (kg/m(2)) of 27.6 +/- 1.4. All food was provided for 6 mo in diets controlled for confounding variables, and subjects self-administered the plans for 6 additional months. Primary and secondary outcomes included energy intake measured by doubly labeled water, body weight and fatness, hunger, satiety, and resting metabolic rate. RESULTS: All groups consumed significantly less energy during CR than at baseline (P < 0.01), but changes in energy intake, body weight, body fat, and resting metabolic rate did not differ significantly between groups. Both groups ate more energy than provided (eg, 21% and 28% CR at 3 mo and 16% and 17% CR at 6 mo with HG and LG, respectively). Percentage weight change at 12 mo was -8.04 +/- 4.1% in the HG group and -7.81 +/- 5.0% in the LG group. There was no effect of dietary composition on changes in hunger, satiety, or satisfaction with the amount and type of provided food during CR. CONCLUSIONS: These findings provide more detailed evidence to suggest that diets differing substantially in glycemic load induce comparable long-term weight loss.

Wonder what the Quack-Jobs at Nutrisystems would think of this or the mounds of other research that had similar findings. You know, Nutrisystems the people that just discovered the GI Index a few years ago and swear you can eat as much Low Gi Nutrisystems food as you would like whithout gaining weight.

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Old 11-07-2007, 09:41 AM   #2 (permalink)
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Default challenging the validity of the gi index

Excellent article by Aragon. It has been posted here before, but a little refresher is not a bad idea.

Elements Challenging the Validity of the Glycemic Index - AlanAragon.com

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Old 11-07-2007, 06:53 PM   #3 (permalink)
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Quote:
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Percentage weight change at 12 mo was -8.04 +/- 4.1% in the HG group and -7.81 +/- 5.0% in the LG group. There was no effect of dietary composition on changes in hunger, satiety, or satisfaction with the amount and type of provided food during CR. CONCLUSIONS: These findings provide more detailed evidence to suggest that diets differing substantially in glycemic load induce comparable long-term weight loss.
So if I interpret this part correctly, it shows that the group that ate a high GI diet lost more weight w/ less variance than the group that ate a low GI diet. Correct?
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Old 11-07-2007, 07:45 PM   #4 (permalink)
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So if I interpret this part correctly, it shows that the group that ate a high GI diet lost more weight w/ less variance than the group that ate a low GI diet. Correct?
Yes.
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Old 11-08-2007, 12:42 AM   #5 (permalink)
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Alright, let me ask a question or two:

1. Does high GI actually cause a higher insulin spike?
2. If not, where did the concept come from...
3. If it does, then perhaps they need to look at how absorbtion rate might affect...what's the word...lipolisys?
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Old 11-08-2007, 10:09 AM   #6 (permalink)
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Quote:
Originally Posted by Cynic View Post
Alright, let me ask a question or two:

1. Does high GI actually cause a higher insulin spike?
2. If not, where did the concept come from...
3. If it does, then perhaps they need to look at how absorbtion rate might affect...what's the word...lipolisys?
1) GI correlates with II (insulin index) in some foods, but not others. An example low-GI/high-II food is milk & milk products.
2) People like to simplify complex stuff & figure GI always is directly proportional to II, when it's not the case with all foods.
3) GI manipulation has failed at lowering bodyfat, especially in long-term trials. So, examining GI's effect on lipolysis would be redundant.
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Old 11-08-2007, 10:20 AM   #7 (permalink)
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Default gi index

the majority of studies do not indicate a higher level of fat loss in low gi vs high gi

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Old 11-08-2007, 10:25 AM   #8 (permalink)
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I always wondered why eating a donut or pastry gave me a headache and then put me in an energy slump. I had heard about the GI concept, but I figured since those foods have a lot of fat, the idea they were giving me an insulin spike must be wrong.

I guess the lesson is that these interactions in the body are extremely complex and not really understood yet.
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Old 11-08-2007, 08:28 PM   #9 (permalink)
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Quote:
Originally Posted by Alan Aragon View Post
3) GI manipulation has failed at lowering bodyfat, especially in long-term trials. So, examining GI's effect on lipolysis would be redundant.

Alan, you being the food/biochemical process guy...

If insulin is responsible for shuttling glycogen/glucose to the body, which hormones are involved in lipolisys?
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Old 11-09-2007, 01:05 PM   #10 (permalink)
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I am not Alan but i think this the answer you are looking for.

Primary hormones directly effecting fat cell breakdown are adrenaline and nor-adrenaline

This article gives an in-depth look at fat breakdwon
Fat Burning How it Works
Max Condition Training and Fitness: Fat Burning How it Works

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Old 11-09-2007, 02:10 PM   #11 (permalink)
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Gi correlates with II in some foods but:
from mendosa.com:

There are some instances, however, where a food has a low glycemic value but a high insulin index value. This applies to dairy foods and to some highly palatable energy-dense "indulgence foods." Some foods (such as meat, fish, and eggs) that contain no carbohydrate, just protein and fat (and essentially have a GI value of zero), still stimulate significant rises in blood insulin.

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Old 11-09-2007, 05:56 PM   #12 (permalink)
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Quote:
Originally Posted by Cynic View Post
Alan, you being the food/biochemical process guy...

If insulin is responsible for shuttling glycogen/glucose to the body, which hormones are involved in lipolisys?
See Jamie's link, that should tell you more than you need to know - thanks Jamie.
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Old 11-09-2007, 11:01 PM   #13 (permalink)
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Thank you coach Hale!

I am starting to lose it on the different measures of insulin response.

So, the currents are:

1. GI - Glycemic Index.
2. GL - Glycemic Load.
3. II - Insulin Index.

Now, if I remember right, GI is measures more of an impulse or spike type affect. Glycemic load measures the total insulin affect for the lifetime of the food.

Where does II fit in?
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Old 11-10-2007, 09:26 AM   #14 (permalink)
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excerpts from The Carbohydrate Files (Hale 2007)

"The glycemic load
Researchers at Harvard University came up with the glycemic load (GL) concept in 1997. The glycemic load is calculated by multiplying the GI value of a food by the amount of (active) carbohydrates per serving and dividing by 100."

Insulin index
The insulin index is a ratio based on insulin levels found over two hours after consuming 1000 calories of the test food to 1000 calories of white bread."

I would recommend you purchase The Carbohydrate Files and Knowledge and Nonsense: the science of nutrition and exercise .For a further explaination of the above-mentioned.

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Old 11-10-2007, 12:10 PM   #15 (permalink)
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From a diabetic point of view GI and GL are often not particularly helpful. Mendosa has liked them. Dr Bernstein says if you are using insulin whether the glucose comes in fast or slow you still have to medicate for it. And if you are trying for tight control it is just better to be very low carb.
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Old 11-10-2007, 12:16 PM   #16 (permalink)
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Quote:
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I would recommend you purchase The Carbohydrate Files and Knowledge and Nonsense: the science of nutrition and exercise .For a further explaination of the above-mentioned.
Thanks Coach, but I really do like to hear it from a human. These books tend to be a bit...sleep inducing, if you get my meaning.

I still haven't made it 1/4 of the way through McGill's "Ultimate Back Fitness and Performance" and I've had the book for a year now. I just tend to doze off reading it.
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Old 11-10-2007, 09:19 PM   #17 (permalink)
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Cynic,

One of the main take-away points I hope you get from this thread is that GI, GL, & II have not proven themselves as useful tools to give a crap about.
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Old 11-11-2007, 11:18 AM   #18 (permalink)
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