Quote:
Originally Posted by cycomiko
Six subjects per group is not much of a concern as their method provides relatively low variability and provides adequate statistical power from that number (the joy of crossover trials)
12 sets of exercise for the legs with teh aim of eliciting failure within 8-10 reps with 2minutes between sets is reasonably representative of a single training session. I know I go nowhere near 12 sets, let alone 12 sets to failure.
|
Yeah, but that's fine for a 30-minute training session involving the legs. I'm wondering what sort of extra demand a training bout with double that volume would impose, given the common practice of training more than one muscle group in a single session, and to what degree that extra demand might raise the ceiling of protein synthesis using a higher dose. Regardless of that speculation, my main issue here is with the authors' implication of a maximally effective protein dose of 100-120g/day (20g administered 5-6x a day).
Quote:
|
Interestingly enough, the dosage that achieved the peak muscle FSR is pretty much inline with earlier work that measured peak rates of protein synthesis at rest with administration of essential amino acids (which work backwards to a dose of WPI around 18grams - for the same weight)
|
I'm assuming you're talking about this trial (correct me if I'm wrong):
http://ajpendo.physiology.org/cgi/co...ull/276/4/E628
From the text: "Subjects had not participated in a resistance exercise training program for >1 yr before participating in the study and were instructed not to change their activity patterns for the duration of the study."
And again, the training protocol was pretty minimal in terms of total work, which was 9 sets for the legs, done in less than 30 minutes.
Quote:
|
But protein synthesis is only one endpoint to measure...
|
Agreed completely. I'd love to see this type of work carried out long-term using higher-volume training session involving more than a single muscle group. Aaron, serious Q here, what would you like to see in terms of design improvement with this particular line of investigation?