I don't know if sugar substitutes signals hunger or not, but I do know that I used to find that if I drank diet soda, I'd then crave something salty/crunchy after. And then the salty thing would make me crave more diet soda. It was a vicious circle of diet soda and Doritos, literally. Oddly, when finally I gave up the diet soda in favor of water, it was relatively easy to give up the Doritos.
So I mostly stay away from diet soda these days. But I do use protein powder that contains Splenda. And it doesn't seem to trigger hunger signals. FWIW.
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