I've been taking a glucosamine/chondroitin blend (500/400 mg, 3x per day) for several years. My goal was to address back pain (arthritis). Towards the end of last year I decided the stuff wasn't helping my back any so I went off it. And my knees really started bothering me. So I went back on the stuff. Purely antidotal, and I wouldn't discount the placebo effect, but I think the stuff helps my knees. Doesn't do anything for my back that I can tell though. The t-mag article's comments about glucosamine possibly causing fat gain is interesting. I've added a lot of fat while I've been on the supplement.
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