Thread: Fat & Happy?
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Old 08-23-2008, 08:41 PM   #20 (permalink)
Bytsi
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Just a note: LD mentioned psych meds and weight gain, and that his doctor thinks the weight gain is because depressed people "wallow" and then start to eat again once they feel better...

There is a chemical process associated with anti-depressants that causes the increase in weight - it's not just eating more because they feel happier. Two anti-depressants (wellbutrin and effexor) are not associated with weight gain because they work on a different pathway.

The main cause of the weight gain (particularly with older tricyclic antidepressants) was their histamine binding properties which led to increased appetite. SSRIs (like prozac and paxil) are better, but still have varying degrees of anti-histamine activity (depending on which one you take) which is a direct physical cause of increased appetite and weight gain.

Just FYI - it's not as simple as eating more because you're happier.
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