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Old 07-03-2008, 01:13 AM   #10 (permalink)
LisaS
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Join Date: Nov 2006
Location: Orange Cty, CA
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Glucogon: liver and perhaps a few other cell types - but not skeletal muscle.

In muscle, adrenaline plays a triggering role - and adrenaline would be present in the blood in greater amounts with exercise, danger (fight/flight), etc.

Also, locally within the cell, the presence of molecules like AMP (which would indicate lots of activity breaking down ATP) will cause some shape-shifting of the enzymes to favor glycogen breakdown.
Also, in active tissue, the concentration of Ca++ can increase - which also makes glycogen breakdown favorable.
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