I successfully integrated NROL and 5k training this past spring and summer. I put on some weight and added strength through it as well. Some others here have integrated it with everything from 5k training to marathons. Honestly though you will have to sacrifice and little at both ends... meaning you won't get the most out of NROL or your running but for those of us that do it the benefits of being well conditioned (not just being able to run) is worth the trade off.
I was able to work up to NROL 3 days a week and 3 days dedicated to running (an interval session, a tempo run and an easy run) but that was only 5k training. If you wanted to add more miles you might need to drop to a 2-days per week lifting schedule. It really depends on your ability to recover.
I would start out slow by taking some days for easy runs and doing the break-in phase 2 days a week. See how you feel after 2-3 weeks and progress from there.
Good Luck
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