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Old 07-07-2007, 11:04 AM   #6 (permalink)
RyPat
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Join Date: Nov 2006
Location: Lexington, KY
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Ok, now I have a serious question/comment. In reference to low carbohydrate diets and the "fat burns in the flame of carbohydrate"--how true is that really?

Can't your body use Pyruvate to make both Acetyl-CoA and Oxaloacetate to enter the Krebs cycle, thus bypassing glycolysis? Pyruvate can be made from Amino Acids (like alanine) and I found on wikipedia that aspartate can also be converted to OOA. So with proper contributions from proteins to make pyruvate and OOA and fats via beta oxidation making ACoA (ultimately), is there any problem with a low carbohydrate diet.

Also, wouldn't contributions from gluconeogenic proteins like glutamine offer glucose for the Krebs cycle? And would it be more proper to say the body burns fat in the flame of carbohydrate preferably? The whole process without carbohydrates seems metabolically inefficient, but in terms of fat loss, that’s a good thing. I think.

Fill in the gaps and correct me if I'm wrong...i'm a little rusty on my biochem.
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