I, too, have an ankle issue due to a sprain. I sprained it all the way back in December 2005. Admittedly, I was back lightly jogging on it within a month, but well over a year later, it still bothers me after any run 10-12 miles or longer. I just pop some ibuprofen. 
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“Life is a headlong rush into the unknown. We can hunker down and hope nothing hits us or we can stand tall, lean into the wind and say, ‘Bring it on, darlin', and don't be stingy with the jalapeños."
-J.M. “Red” Spicer
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