I think so; I do it pretty regularly. I also often use 3-4 minutes as the first part of my pre-lifting warmup; it helps to get things heated up quickly. If you're new to it, however, I'd ease into it. If you do 15 minutes right off, you may feel it the next day or two in unpleasant ways.
Make sure you jump/skip on a padded surface or a surface with some "give", and do small jumps on the balls of your feet, trying to land softly.
You might find you will do intervals (a minute or two, and 30 sec or a minute rest) until you build up to 10 mins or more of continuous skipping.
You can also try 2-3 minutes of skipping, and then some other activity, like 10 pushups and 10 situps, or some stretching, and then repeat that cycle 5 times. Be creative and have fun with it.
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